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Population-Based Incidence of Conjunctival Melanoma in Various Races and Ethnic Groups and Comparison With Other Melanomas
- Source :
-
American Journal of Ophthalmology . Mar2008, Vol. 145 Issue 3, p418-423. 6p. - Publication Year :
- 2008
-
Abstract
- Purpose: To investigate racial and ethnic differences in the incidence of conjunctival melanoma in a large population-based study. Design: Observational cross-sectional study. Methods: Using data from 1992 through 2003 provided by the National Cancer Institute’s Surveillance, Epidemiology, and End Results (SEER) program, we calculated age-adjusted incidence rates of conjunctival melanoma in various racial and ethnic groups (Black, American Indian, Asian and Pacific Islander, Hispanic, and non-Hispanic White). In addition, we calculated the standard incidence ratios (risk ratios) and 95% confidence intervals to describe the differences within these racial and ethnic groups. Results: From 1992 through 2003, there were a total of 168 conjunctival melanomas diagnosed in 13 SEER registries with known racial and ethnic groups. The annual age-adjusted incidence rates (per million population) of conjunctival melanoma was 0.18 (Blacks), 0.17 (American Indians), 0.15 (Asians), 0.33 (Hispanics), and 0.49 (non-Hispanic Whites). The difference in the incidence of conjunctival melanoma between Whites and Blacks or Asians was statistically significant, but was not significant between Blacks and Asians. Conclusions: The overall White-to-Black incidence ratio in conjunctival melanoma was 2.6:1, which is much less than that of uveal melanoma (18:1) and cutaneous melanoma (13:1 to 26:1), but is similar to that of mucosal melanoma (2.2:1 to 2.3:1). The cause and significance of this difference of racial and ethnic incidence in various melanomas are discussed. [Copyright &y& Elsevier]
- Subjects :
- *ETHNIC groups
*CAUCASIAN race
*PUBLIC health
*OPHTHALMOLOGY
Subjects
Details
- Language :
- English
- ISSN :
- 00029394
- Volume :
- 145
- Issue :
- 3
- Database :
- Academic Search Index
- Journal :
- American Journal of Ophthalmology
- Publication Type :
- Academic Journal
- Accession number :
- 30068165
- Full Text :
- https://doi.org/10.1016/j.ajo.2007.10.022