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Experience with the Platelia Candida ELISA for the diagnosis of invasive candidosis in neonatal patients.

Experience with the Platelia Candida ELISA for the diagnosis of invasive candidosis in neonatal patients.

Authors :
Oliveri, S.
Trovato, L.
Betta, P.
Romeo, M. G.
Nicoletti, G.
Source :
Clinical Microbiology & Infection. Apr2008, Vol. 14 Issue 4, p391-393. 3p. 1 Chart, 1 Graph.
Publication Year :
2008

Abstract

This preliminary study evaluated the use of the Platelia Candida antigen kit for the diagnosis of invasive candidosis in 70 of 184 pre-term infants admitted to a neonatal intensive care unit between March 2004 and March 2006. The frequency of confirmed candidaemia was 6.5%. The sensitivity and specificity of the assay were 94.4% and 94.2%, respectively, with a positive predictive value of 85% and a negative predictive value of 98%. These results suggest that the inclusion of regular serological surveillance for mannanaemia in some pre-term infants would complement blood cultures for the early detection of candidosis. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
1198743X
Volume :
14
Issue :
4
Database :
Academic Search Index
Journal :
Clinical Microbiology & Infection
Publication Type :
Academic Journal
Accession number :
31180787
Full Text :
https://doi.org/10.1111/j.1469-0691.2007.01938.x