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The Dewar photoproduct of thymidylyl(3'...5')-thymidine (Dewar product) exhibits mutagenic behavior in accordance with the `A rule.'.

Authors :
Lee, Joon-Hwa
Bae, Sung-hun
Source :
Proceedings of the National Academy of Sciences of the United States of America. 04/25/2000, Vol. 97 Issue 9, p4591. 6p. 4 Diagrams, 1 Chart.
Publication Year :
2000

Abstract

Presents information on a study which used experimental nuclear magnetic resonance restraints and molecular dynamics to determine the solution structure of a Dewar-lesion DNA decamer duplex. Structure determination; Hydrogen-binding feature at the Dewar lesion site; Methodology of the study; Results and discussion.

Details

Language :
English
ISSN :
00278424
Volume :
97
Issue :
9
Database :
Academic Search Index
Journal :
Proceedings of the National Academy of Sciences of the United States of America
Publication Type :
Academic Journal
Accession number :
3173357
Full Text :
https://doi.org/10.1073/pnas.080057097