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Somatosensory-evoked fields on magnetoencephalography for epilepsy infants younger than 4 years with total intravenous anesthesia
- Source :
-
Clinical Neurophysiology . Jun2008, Vol. 119 Issue 6, p1328-1334. 7p. - Publication Year :
- 2008
-
Abstract
- Abstract: Objective: Patients must remain immobile for magnetoencephalography (MEG) and MRI recordings to allow precise localization of brain function for pre-surgical functional mapping. In young children with epilepsy, this is accomplished with recordings during sleep or with anesthesia. This paper demonstrates that MEG can detect, characterize and localize somatosensory-evoked fields (SEF) in infants younger than 4 years of age with or without total intravenous anesthesia (TIVA). Methods: We investigated the latency, amplitude, residual error (RE) and location of the N20m of the SEF in 26 infants (mean age=2.6 years). Seventeen patients underwent TIVA and 9 patients were tested while asleep, without TIVA. Results: MEG detected 44 reliable SEFs (77%) in 52 median nerve stimulations. We found 27 reliable SEFs (79%) with TIVA and 13 reliable SEFs (72%) without TIVA. TIVA effects included longer latencies (p <0.001) and lower RE (p <0.05) compared to those without TIVA. Older patients and larger head circumferences also showed significantly shorter latencies (p <0.01). Conclusions: TIVA resulted in reliable SEFs with lower RE and longer latencies. Significance: MEG can detect reliable SEFs in infants younger than 4 years old. When infants require TIVA for MEG and MRI acquisition, SEFs can still be reliably observed. [Copyright &y& Elsevier]
Details
- Language :
- English
- ISSN :
- 13882457
- Volume :
- 119
- Issue :
- 6
- Database :
- Academic Search Index
- Journal :
- Clinical Neurophysiology
- Publication Type :
- Academic Journal
- Accession number :
- 31925272
- Full Text :
- https://doi.org/10.1016/j.clinph.2008.02.018