Participation behaviour following a false positive test in the Copenhagen mammography screening programme.

Introduction. There is an ongoing debate concerning possible disadvantages of mammography screening, one being the consequence of receiving a false positive test-result. It is argued that receiving a false positive answer may have short- and/or long-term adverse psychological effects on women, but results from different studies are conflicting. We tested if there was a difference in continued participation behaviour between the group of women who have been subject to a false positive result and those who have not. Material and methods. The study used the registers from the first six invitation rounds of the mammography screening programme in Copenhagen (1991-2003). We estimated the relative risk of not participating in the subsequent screening round for women with a false positive test using women with a negative test as baseline. As outcome measure odds ratios (OR) with 95% confidence intervals (CI) were used. Results. There was no significant difference in participation in the subsequent round between women with a false positive test and women with a negative test. The proportion of screens resulting in false positive answers, both after assessment and after surgery, decreased from 5.54% in Round 1 to 1.79% in Round 5. Participation in the subsequent screening round was well above 80% in all five screening rounds. Discussion. Our results showed that women experiencing a false positive test at mammography screening participated in the subsequent screening round to the same extent as did women experiencing a negative screening test, regardless of whether the false positive statement was given following assessment or following surgery. The benign to malignant biopsy ratio, comparing the type B false positives to the true positives, was by the fifth round well below the desirable level of ≤1:4, recommended by the European guidelines. Other possible adverse effects should be further investigated. [ABSTRACT FROM AUTHOR]