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Microwave-Induced Synthesis of Schiff Bases of Aminothiazolyl Bromocoumarins as Antibacterials.

Authors :
Venugopala, K. N.
Jayashree, B. S.
Source :
Indian Journal of Pharmaceutical Sciences. 2008, Vol. 70 Issue 1, p88-91. 4p. 1 Diagram, 3 Charts.
Publication Year :
2008

Abstract

A fast and highly efficient method for the synthesis of some of the schiff bases of aminothiazolylbromocoumarin (4a-m) has been performed by microwave irradiation of 2'-amino-4'-(6-bromo-3-coumarinyl) thiazole (3) and substituted aromatic aldehydes (a-m). Microwave assisted reactions have resulted in better yields of the desired products than when prepared under conventional conditions. The resulting products were evaluated for their qualitative and quantitative antibacterial activity. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
0250474X
Volume :
70
Issue :
1
Database :
Academic Search Index
Journal :
Indian Journal of Pharmaceutical Sciences
Publication Type :
Academic Journal
Accession number :
32023276
Full Text :
https://doi.org/10.4103/0250-474X.40338