Participation of 5-Hydroxytryptamine in Pain-Related Behavior Induced by Nucleus Pulposus Applied on the Nerve Root in Rats.

Authors :: Kato, Kinshi
Kikuchi, Shin-ichi
Konno, Shin-ichi
Sekiguchi, Miho
Source :: Spine (03622436). 5/20/2008, Vol. 33 Issue 12, p1330-1336. 7p. 3 Black and White Photographs, 3 Graphs.
Publication Year :: 2008
Abstract: The article reports on the evaluation of the effects of exogenous five-hydroxytryptamine (5-HT) applied on the nerve root on pain-related behavior, the release of endogenous 5-HT in plasma and the expression of receptors in dorsal root ganglion in a rat lumbar disc hermiation model. Exogenous 5-HT to the nerve root induced pain-related behavior compared with the nucleus pulposus application.

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