Drug Screening of Hair by Liquid Chromatography— Tandem Mass Spectrometry.

The article presents a study on drug screening of hair using liquid chromatography-tandem mass spectrometry. It is implied that hair has become a relevant matrix for drug analysis which is complementary to blood and urine as a matrix. Methods of the study include a long-term detection window which makes hair analysis fitted for the detection of illegal and medicinal drugs exposure for twelve months. Within the given period, liquid chromatography-tandem mass spectrometry (LC-MS-MS) method was validated through the use of internal standards, ion mode electrospray LC-MS-MS, and drugs or metabolites. Results show that LC-MS-MS method proved to be simple and robust in identifying drugs in hair.