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Reactions With Hydrazonoyl Halides 591: Synthesis and Antimicrobial Activity of 2,3-Dihydro-1,3,4-thiadiazole, Triazolino[4,3-a]pyrimidine, and Pyrimido[1,2-b][1,2,4,5]tetrazin-6-one Containing Benzofuran Moiety.

Authors :
Abdelhamid, Abdou O.
Mohamed, Mahmoud A.
Zaki, Yasser H.
Source :
Phosphorus, Sulfur & Silicon & the Related Elements. Jul2008, Vol. 183 Issue 7, p1746-1754. 9p. 4 Diagrams, 3 Charts.
Publication Year :
2008

Abstract

2,3-Dihydro-1,3,4-thiadiazole, triazolino[4,3-a]pyrimidine and pyrimido[1,2-b][1,2,4,5]tetrazin-6-one containing benzofuran Moiety were synthesized from C-benzofuran-2-yl-N-phenylhydrazonoyl bromides, and the appropriate alkyl arylidenehydrazinecabodithioates and pyrimidine-2-thione and N-aminopyrimidine-2-thione, respectively. All structures of the newly synthesized compounds were elucidated by elemental analysis, spectral data, and alternative synthetic methods whenever possible. Newly compounds are capable of high inhibiting the growth of bacteria (gram positive and gram negative). [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
10426507
Volume :
183
Issue :
7
Database :
Academic Search Index
Journal :
Phosphorus, Sulfur & Silicon & the Related Elements
Publication Type :
Academic Journal
Accession number :
32771422
Full Text :
https://doi.org/10.1080/10426500701734265