Back to Search
Start Over
A novel approach to the taxane ABC ring system through chemical conversion from C19-diterpenoid alkaloid deltaline
- Source :
-
Tetrahedron . Aug2008, Vol. 64 Issue 32, p7594-7604. 11p. - Publication Year :
- 2008
-
Abstract
- Abstract: A novel approach to the highly functionalized taxane ABC ring system through chemical conversion of the C19-diterpenoid alkaloid deltaline (1) was achieved in six steps (1→17) in 18% overall yield mainly by Grob fragmentation, fission of the Δ9(14) double bond, followed by aldol condensation, and Pelletier''s cleavage process. [Copyright &y& Elsevier]
- Subjects :
- *CONDENSATION
*ALKALOIDS
*PLANT metabolites
*MICROBIAL metabolites
Subjects
Details
- Language :
- English
- ISSN :
- 00404020
- Volume :
- 64
- Issue :
- 32
- Database :
- Academic Search Index
- Journal :
- Tetrahedron
- Publication Type :
- Academic Journal
- Accession number :
- 32842894
- Full Text :
- https://doi.org/10.1016/j.tet.2008.05.089