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In Vitro Characterization of Borneol Metabolites by GC-MS Upon Incubation with Rat Liver Microsomes.
- Source :
-
Journal of Chromatographic Science . May2008, Vol. 46 Issue 5, p419-423. 5p. - Publication Year :
- 2008
-
Abstract
- The metabolism of borneol is studied by the analysis of incubations of in vitro-prepared rat liver microsomes. A sensitive gas chromatography (GC)–mass spectrometry (MS) method is developed for the identification of borneol and its metabolites. Four novel metabolites, which have not previously been reported, are isolated and confirmed by comparison of the GC–MS method. The biotransformation pathway of borneol in rat liver microsomes is proposed based on the in vitro results. [ABSTRACT FROM AUTHOR]
- Subjects :
- *METABOLITES
*MICROSOMES
*LABORATORY rats
*MASS spectrometry
Subjects
Details
- Language :
- English
- ISSN :
- 00219665
- Volume :
- 46
- Issue :
- 5
- Database :
- Academic Search Index
- Journal :
- Journal of Chromatographic Science
- Publication Type :
- Academic Journal
- Accession number :
- 32952793
- Full Text :
- https://doi.org/10.1093/chromsci/46.5.419