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Botulinum toxin type A as an adjuvant treatment modality for extensive Hailey-Hailey disease.

Botulinum toxin type A as an adjuvant treatment modality for extensive Hailey-Hailey disease.

Authors :
Koeyers, Wendy Jane
Van Der Geer, Simone
Krekels, Gertruud
Source :
Journal of Dermatological Treatment. Aug2008, Vol. 19 Issue 4, p251-254. 4p. 4 Color Photographs.
Publication Year :
2008

Abstract

Background: Extensive Hailey-Hailey disease is often resistant to conventional topical and systemic therapies. The systemic and ablative therapies have many side effects and/or high recurrence rates. Therefore, an alternative safe and effective treatment is needed. Objective: To assess the effectiveness of botulinum toxin type A in the treatment of extensive Hailey-Hailey disease. Methods: The cases of six patients with extensive Hailey-Hailey disease resistant to multiple therapeutic regimens were studied and described. Adjuvant therapy with botulinum toxin type A/Dysport® was started in all six cases. Results: Marked improvement of the lesions was achieved with few side effects in all patients. Conclusion: Botulinum toxin type A is a safe and effective adjuvant treatment for extensive Hailey-Hailey disease. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
09546634
Volume :
19
Issue :
4
Database :
Academic Search Index
Journal :
Journal of Dermatological Treatment
Publication Type :
Academic Journal
Accession number :
33158237
Full Text :
https://doi.org/10.1080/09546630801955135