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Variation in fasting and non-fasting serum enterolactone concentrations in women of the Malmö Diet and Cancer cohort.
- Source :
-
European Journal of Clinical Nutrition . Aug2008, Vol. 62 Issue 8, p1005-1009. 5p. 2 Charts, 1 Graph. - Publication Year :
- 2008
-
Abstract
- Objectives:The aim of this study was to examine the variation of enterolactone from fasting and non-fasting blood of middle-aged healthy women eating a normal diet to determine the usefulness of a single sample in epidemiological studies.Subjects and methods:Twenty-six women born between 1940 and 1950 were recruited within the Malmö Diet and Cancer cohort. Three non-fasting and two overnight fasting samples were collected from each individual during a 5-week period. Twenty-one participated in all measurements. Enterolactone concentrations were analyzed by time-resolved fluoroimmunoassay.Results:The within-subject and between-subject variations (coefficient of variations, CV) were estimated to 59 and 89% respectively for fasting samples and 71 and 67% for non-fasting samples. The intraclass correlation coefficients (ICC) were estimated to 0.66 (95% confidence interval (CI) 0.35–0.84) for fasting and 0.48 (95% CI, 0.22–0.72) for non-fasting samples.Conclusions:Although the estimated ICC for blood samples was moderate, it indicates that enterolactone levels of both fasting and non-fasting blood samples should be useful in future projects within the Malmö Diet and Cancer cohort.European Journal of Clinical Nutrition (2008) 62, 1005–1009; doi:10.1038/sj.ejcn.1602811; published online 30 May 2007 [ABSTRACT FROM AUTHOR]
- Subjects :
- *FASTING
*DIET in disease
*LACTONES
*SERUM
*LIGNANS
*CANCER in women
*IMMUNOASSAY
Subjects
Details
- Language :
- English
- ISSN :
- 09543007
- Volume :
- 62
- Issue :
- 8
- Database :
- Academic Search Index
- Journal :
- European Journal of Clinical Nutrition
- Publication Type :
- Academic Journal
- Accession number :
- 33526054
- Full Text :
- https://doi.org/10.1038/sj.ejcn.1602811