Back to Search
Start Over
Global behaviour of an age-infection-structured HIV model with impulsive drug-treatment strategy
- Source :
-
Journal of Theoretical Biology . Aug2008, Vol. 253 Issue 4, p749-754. 6p. - Publication Year :
- 2008
-
Abstract
- Abstract: In this paper, we develop an HIV model that considers the dependence of HIV/AIDS progress on infection age (duration since infection), chronological age and impulsive antiretroviral treatment. The analytical results show that there exists a globally asymptotically stable infection-free state when the impulsive period and drug-treatment proportion satisfy . The numerical simulation results indicate that there exist and such that . Due to pulses, it would be difficult to obtain the optimal pulse interval in the age distribution of population. However, our results demonstrate the effect of the impulsive drug-treatment strategy on the dynamics of HIV/AIDS. [Copyright &y& Elsevier]
- Subjects :
- *HIV infections
*HIV
*AGE groups
*DEMOGRAPHY
Subjects
Details
- Language :
- English
- ISSN :
- 00225193
- Volume :
- 253
- Issue :
- 4
- Database :
- Academic Search Index
- Journal :
- Journal of Theoretical Biology
- Publication Type :
- Academic Journal
- Accession number :
- 33532706
- Full Text :
- https://doi.org/10.1016/j.jtbi.2008.04.021