Detection of 1-Benzylpiperazine and 1-(3-Trifluoromethylphenyl)-piperazine in Urine Analysis Specimens Using GC—MS and LC—ESI-MS.

The article examines the presence of 1-(3-trifluoromethylphenyl)-piperazine (TFMPP) and 1-benzylpiperazine (BZP) in urine samples using liquid chromatography-electrospray ionization-mass spectrometry (LC-ESI-MS) and gas chromatography-mass spectrometry (GC-MS). The BZP and TFMPP were detected through a full GC-MS scan of the seven U.S. service members' urine analysis specimen. Meanwhile, the LC-ESI-MS confirmed that in selected ion monitoring mode (SIM) yielded urinary concentrations ranging from 13.0 to 429.1 milligram/liter (mg/L) for BZP and 0.79 to 25.4 mg/L for TFMPP.