Failure of Routine HIV-1 Tests in a Case Involving Transmission With Preseroconversion Blood Components During the Infections Window Period.

Authors :: Ai Ee Ling
Robbins, Kenneth E.
Brown, Teresa M.
Dunmire, Valerie
Su Yun Se Thoe
Sin-Yew Wong
Yee Sin Leo
Teo, Diana
Gallarda, James
Phelps, Bruce
Chamberland, Mary E.
Busch, Michael P.
Folks, Thomas M.
Kalish, Marcia L.
Source :: JAMA: Journal of the American Medical Association. 7/12/2000, Vol. 284 Issue 2, p210. 5p. 2 Charts.
Publication Year :: 2000
Abstract: Presents a study designed to determine HIV-1 genetic linkage between virus in 2 HIV-infected recipients of blood components and virus in the donor, who was HIV antigen and antibody negative at the time of donation. Methods; Results; Conclusion that United States HIV nucleic acid amplification (NAT) may not be sufficiently sensitive to detect all infectious window-period donations.

Subjects :: *BLOOD transfusion
*DIAGNOSIS of HIV infections
*BLOOD testing
*BLOOD donors
*PERIODIC health examinations

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