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Successful Multimodal Therapies for a Primary Atypical Teratoid/Rhabdoid Tumor in the Cervical Spine.
- Source :
-
Pediatric Neurosurgery . Aug2008, Vol. 44 Issue 5, p406-413. 8p. 2 Color Photographs, 2 Black and White Photographs, 2 Charts. - Publication Year :
- 2008
-
Abstract
- Atypical teratoid/rhabdoid tumor (AT/RT) occurring in the central nervous system is a high-grade malignant tumor, and its prognosis is poor for patients younger than 3 years of age. In this article, we present a case of infant AT/RT in the cervical spine and its successful treatment by intensive chemotherapy. The patient, a 1.75-year-old girl, developed an acute, progressive tetraparesis. MRI revealed a large, intradural mass in the cervical spine.Total surgical resection was performed, and the specimen was diagnosed as AT/RT. Continuously, she received intensive chemotherapy using thiotepa with autologous bone marrow transplantation. At the age of nearly 3 years, she received radiation therapy to the local tumor bed and craniospinal axis. She is now 4 years old and has been maintained in complete remission with a good clinical course and no neurological deficit. The success of this treatment for the patient was that we could prevent tumor recurrence until she was able to receive radiotherapy. Copyright © 2008 S. Karger AG, Basel [ABSTRACT FROM AUTHOR]
- Subjects :
- *TUMORS
*THERAPEUTICS
*TERATOMA
*CERVICAL vertebrae
*RADIOTHERAPY
Subjects
Details
- Language :
- English
- ISSN :
- 10162291
- Volume :
- 44
- Issue :
- 5
- Database :
- Academic Search Index
- Journal :
- Pediatric Neurosurgery
- Publication Type :
- Academic Journal
- Accession number :
- 34017741
- Full Text :
- https://doi.org/10.1159/000149910