Magnetically Separable Pd Catalyst for Carbonylative Sonogashira Coupling Reactions for the Synthesis of α,β-Alkynyl Ketones.

A magnetically separable palladium catalyst was simply synthesized through a wet impregnation incorporating palladium nanoparticles and superparamagnetic Fe 3O 4nanoparticles in KBH 4solution, which is a highly efficient catalyst for the carbonylative Sonogashira coupling reaction of aryl iodides with terminal alkynes under phosphine-free conditions. This catalyst is completely magnetically recoverable due to the super paramagnetic behavior of Fe 3O 4and can be reused with sustained selectivity and activity. [ABSTRACT FROM AUTHOR]