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Roles of BRCA1 and its interacting proteins.

Authors :
Chu-Xia Deng
Brodie, Steven G.
Source :
BioEssays. Aug2000, Vol. 22 Issue 8, p728. 10p. 3 Diagrams, 1 Chart.
Publication Year :
2000

Abstract

Focuses on a study that examined the significance of the interactions between the breast cancer associated gene 1 (BRCA1) and other proteins. Role of the germline mutations of BRCA1 in breast and ovarian cancers; Roles of the BRCA1 tumor suppressor gene in several cellular pathways; Involvement of BRCA1 in DNA-damage repair and centrosome duplication.

Details

Language :
English
ISSN :
02659247
Volume :
22
Issue :
8
Database :
Academic Search Index
Journal :
BioEssays
Publication Type :
Academic Journal
Accession number :
3465932
Full Text :
https://doi.org/10.1002/1521-1878(200008)22:8<728::AID-BIES6>3.0.CO;2-B