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Cu(OTf)2/trisoxazoline catalyzed asymmetric Friedel–Crafts reaction of pyrroles with alkylidene malonates

Authors :
Cao, Chun-Li
Zhou, You-Yun
Sun, Xiu-Li
Tang, Yong
Source :
Tetrahedron. Nov2008, Vol. 64 Issue 47, p10676-10680. 5p.
Publication Year :
2008

Abstract

Abstract: In the presence of catalytic amount of Cu(OTf)2/trisoxazoline, an enantioselective Friedel–Crafts reaction of N-methyl pyrrole with alkylidene malonates has been developed and up to 66% ee is achieved. [Copyright &y& Elsevier]

Details

Language :
English
ISSN :
00404020
Volume :
64
Issue :
47
Database :
Academic Search Index
Journal :
Tetrahedron
Publication Type :
Academic Journal
Accession number :
34742902
Full Text :
https://doi.org/10.1016/j.tet.2008.09.023