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Epigenome dynamics: a quantitative genetics perspective.
- Source :
-
Nature Reviews Genetics . Nov2008, Vol. 9 Issue 11, p883-890. 8p. 4 Diagrams. - Publication Year :
- 2008
-
Abstract
- Classically, quantitative geneticists have envisioned DNA sequence variants as the only source of heritable phenotypes. This view should be revised in light of accumulating evidence for widespread epigenetic variation in natural and experimental populations. Here we argue that it is timely to consider novel experimental strategies and analysis models to capture the potentially dynamic interplay between chromatin and DNA sequence factors in complex traits. [ABSTRACT FROM AUTHOR]
- Subjects :
- *NUCLEOTIDE sequence
*PHENOTYPES
*EPIGENESIS
*CHROMATIN
*QUANTITATIVE genetics
Subjects
Details
- Language :
- English
- ISSN :
- 14710056
- Volume :
- 9
- Issue :
- 11
- Database :
- Academic Search Index
- Journal :
- Nature Reviews Genetics
- Publication Type :
- Academic Journal
- Accession number :
- 34782454
- Full Text :
- https://doi.org/10.1038/nrg2467