Pathophysiology of Rheumatoid Arthritis: Split or Lump?

The author reflects on the pathophysiogical aspects of rheumatoid arthritis (RA). He challenges the traditional view of the disease and argues on the unnecessary view of J. R. Kirwan on split and on the intriguing details of the study by A. K. Brown. He views that subclinical joint information shown by ultrasound and magnetic resonance imaging (MRI) best explains the structural deterioration of RA patients.