A Search for Subgroups of Patients With ARDS Who May Benefit From Surfactant Replacement Therapy.

The article presents a study on the search for subgroups of Adult Respiratory Distress Syndrome (ARDS) patients who can benefit from recombinant surfactant protein-surfactant (rSP-C) surfactant therapy. A pooled analysis of five multicenter studies of ARDS patients treated with rSP-C surfactant was made and factors were observed using logistic regression analysis and multivariate analysis. Results show that rSP-C surfactant treatment ameliorated oxygenation but had no effect on mortality.