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Greatly reduced amino acid alphabets in directed evolution: making the right choice for saturation mutagenesis at homologous enzyme positions.
- Source :
-
Chemical Communications . Nov2008, Vol. 2008 Issue 43, p5499-5501. 3p. - Publication Year :
- 2008
-
Abstract
- Enantioselective mutants of the thermally robust phenyl acetone monooxygenase (PAMO) as catalysts in Baeyer–Villiger reactions have been evolved by utilizing saturation mutagenesis in which drastically reduced amino acid alphabets are employed at homologous enzyme positions. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 13597345
- Volume :
- 2008
- Issue :
- 43
- Database :
- Academic Search Index
- Journal :
- Chemical Communications
- Publication Type :
- Academic Journal
- Accession number :
- 35144299
- Full Text :
- https://doi.org/10.1039/b813388c