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Fullerene Water Suspension (nC60) Exerts Antibacterial Effects via ROS-Independent Protein Oxidation.
- Source :
-
Environmental Science & Technology . 11/1/2008, Vol. 42 Issue 21, p8127-8132. 6p. - Publication Year :
- 2008
-
Abstract
- Buckminsterfullerene (C60) can form water suspensions (nC60) that exert toxic effects. While reactive oxygen species (ROS) generation has been implicated as the mechanism for mammalian cytotoxicity, we propose that nC60 exerts ROS-independent oxidative stress in bacteria, with evidence of protein oxidation, changes in cell membrane potential, and interruption of cellular respiration. This mechanism requires direct contact between the nanoparticle and the bacterial cell and differs from previously reported nanomaterial antibacterial mechanisms that involve ROS generation (metal oxides) or leaching of toxic elements (nanosilver). [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 0013936X
- Volume :
- 42
- Issue :
- 21
- Database :
- Academic Search Index
- Journal :
- Environmental Science & Technology
- Publication Type :
- Academic Journal
- Accession number :
- 35406014
- Full Text :
- https://doi.org/10.1021/es801869m