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Association between the SERPING1 gene and age-related macular degeneration: a two-stage case-control study.
- Source :
-
Lancet . 11/22/2008, Vol. 372 Issue 9652, p1828-1834. 7p. 1 Black and White Photograph. - Publication Year :
- 2008
-
Abstract
- This article discusses research into the genetic aspects of age-related macular degeneration. The genetic screening of British patients with age-related macular degeneration for single nucleotide polymorphisms (SNP) that indicate possible genotypic contributors to the disease is described. The SNP of rs2511989 in intron six of the SERPING1 gene is presented as variation associated with age-related macular degeneration. the location of SNPs correlated with age-related macular degeneration on SERPING1 is considered. Reverse transcriptase polymerase chain reaction testing of mRNA from SERPING1 is used to indicate its association with retinal proteins.
Details
- Language :
- English
- ISSN :
- 01406736
- Volume :
- 372
- Issue :
- 9652
- Database :
- Academic Search Index
- Journal :
- Lancet
- Publication Type :
- Academic Journal
- Accession number :
- 35663070
- Full Text :
- https://doi.org/10.1016/S0140-6736(08)61348-3