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Total synthesis of (+)-acutiphycin and (+)-trans-20,21-didehydroacutiphycin.
- Source :
-
Journal of the American Chemical Society . 11/12/97, Vol. 119 Issue 45, p10935. 12p. - Publication Year :
- 1997
-
Abstract
- Discusses the synthesis of the cytotoxic macrolides (+)-acutiphycin and (+)-trans-20,21-didehydroacutiphycin. Construction of common advanced aldehyde; Synthesis of vinyl bromides; Methods for macrolactone generation; Metabolites produced by the source of the blue-green alga Osillatoria acutissima.
- Subjects :
- *MACROLIDE antibiotics
*BIOSYNTHESIS
Subjects
Details
- Language :
- English
- ISSN :
- 00027863
- Volume :
- 119
- Issue :
- 45
- Database :
- Academic Search Index
- Journal :
- Journal of the American Chemical Society
- Publication Type :
- Academic Journal
- Accession number :
- 35887
- Full Text :
- https://doi.org/10.1021/ja972497r