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Stereoselective synthesis of (+)-secosyrin 1
- Source :
-
Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry . Apr2009, Vol. 50 Issue 15, p1693-1695. 3p. - Publication Year :
- 2009
-
Abstract
- Abstract: A Chiron approach for the synthesis of (+)-secosyrin 1 from d-mannitol has been described. The key steps are a stereoselective Wittig reaction and an intramolecular Michael addition on the disubstituted butenolide, leading to a highly stereoselective formation of the tertiary chiral centre of (+)-secosyrin 1. [Copyright &y& Elsevier]
Details
- Language :
- English
- ISSN :
- 00404039
- Volume :
- 50
- Issue :
- 15
- Database :
- Academic Search Index
- Journal :
- Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 36767257
- Full Text :
- https://doi.org/10.1016/j.tetlet.2009.01.106