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Synthesis of (−)-lobeline via enzymatic desymmetrization of lobelanidine
- Source :
-
Bioorganic & Medicinal Chemistry . Mar2009, Vol. 17 Issue 5, p1837-1839. 3p. - Publication Year :
- 2009
-
Abstract
- Abstract: The bioactive alkaloid (−)-lobeline was synthesized via the stereoselective acylation (desymmetrization) of meso-lobelanidine by vinyl acetate in the presence of Candida antarctica lipase B. [Copyright &y& Elsevier]
Details
- Language :
- English
- ISSN :
- 09680896
- Volume :
- 17
- Issue :
- 5
- Database :
- Academic Search Index
- Journal :
- Bioorganic & Medicinal Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 36767837
- Full Text :
- https://doi.org/10.1016/j.bmc.2009.01.055