Alternate Selectivity for Polar Compounds in Hydrophilic Interaction Liquid Chromatography (HILIC) Using a New Amino Type HILIC Column.

Hydrophilic interaction liquid chromatography (HILIC) offers unique advantages for the separation of very polar compounds when compared to reversed-phase chromatography. A new silica based HILIC phase was developed to provide additional selectivity options in HILIC separations, The separation of water soluble vitamins on the new TSKgel NH2-1OO HIUC column and on the well known TSKgel Amide-80 HILIC column demonstrates the differences in selectivity. [ABSTRACT FROM AUTHOR]