Sialylation reactions with N,N-acetyl, benzoyl-O-perbenzoyl-protected sialyl donor

Authors :: Wang, Yue
Ye, Xin-Shan
Source :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry. Jul2009, Vol. 50 Issue 27, p3823-3826. 4p.
Publication Year :: 2009
Abstract: Abstract: A new sialyl donor, N,N-acetyl, benzoyl-O-perbenzoyl-protected p-toluenethiosialoside, was synthesized and its sialylation reaction was investigated. This reaction proceeded in dichloromethane and β anomeric selectivity was achieved when NIS–TfOH was used as promoter. This method may be employed to construct the unnatural β-linked sialosides. [Copyright &y& Elsevier]

Subjects :: *CHEMICAL reactions
*ORGANIC synthesis
*DICHLOROMETHANE
*GLYCOSYLATION
*CARBOHYDRATES
*STEREOCHEMISTRY

Language :: English
ISSN :: 00404039
Volume :: 50
Issue :: 27
Database :: Academic Search Index
Journal :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry
Publication Type :: Academic Journal
Accession number :: 40112655
Full Text :: https://doi.org/10.1016/j.tetlet.2009.04.034

Full Text Access

Tools