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Oligopeptide-modified silicon nanowire arrays as multichannel metal ion sensors
- Source :
-
Biosensors & Bioelectronics . Jul2009, Vol. 24 Issue 11, p3248-3251. 4p. - Publication Year :
- 2009
-
Abstract
- Abstract: Semiconducting nanowires have the potential to function as highly sensitive and selective sensors for label-free detection of biological and chemical species. In this paper, we describe the preparation and applications of oligopeptide-modified single crystal silicon nanowire (SiNW) arrays as multichannel metal ion sensors. Because these SiNW arrays were fabricated by using a “top-down” process, a very high density of individually addressable SiNW (180 SiNWs grouped into 36 clusters) can be manufactured on a single chip. Furthermore, after two different SiNW clusters are modified with Pb2+-selective and Cu2+-selective oligopeptide, respectively, concentrations of Pb2+ and Cu2+ in aqueous solutions can be detected simultaneously and selectively in two different channels. By using the SiNW arrays, we successfully achieved a detection limit of 1nM for Pb2+ and 10nM for Cu2+, respectively. These results demonstrate the potential utility of oligopeptide-modified SiNW arrays for highly sensitive and selective chemical and biological sensing applications. [Copyright &y& Elsevier]
- Subjects :
- *NANOWIRES
*OLIGOPEPTIDES
*BIOSENSORS
*METAL ions
*CHEMICAL detectors
*SEMICONDUCTORS
Subjects
Details
- Language :
- English
- ISSN :
- 09565663
- Volume :
- 24
- Issue :
- 11
- Database :
- Academic Search Index
- Journal :
- Biosensors & Bioelectronics
- Publication Type :
- Academic Journal
- Accession number :
- 41241051
- Full Text :
- https://doi.org/10.1016/j.bios.2009.04.007