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Imaging Transcription in Living Cells.

Authors :
Darzacq, Xavier
Jie Yao
Larson, Daniel R.
Causse, Sébastien Z.
Bosanac, Lana
de Turris, Valeria
Ruda, Vera M.
Lionnet, Timothee
Zenklusen, Daniel
Guglielmi, Benjamin
Tjian, Robert
Singer, Robert H.
Source :
Annual Review of Biophysics. 2009, Vol. 38, p173-196. 24p.
Publication Year :
2009

Abstract

The advent of new technologies for the imaging of living cells has made it possible to determine the properties of transcription, the kinetics of polymerase movement, the association of transcription factors, and the progression of the polymerase on the gene. We report here the current state of the field and the progress necessary to achieve a more complete understanding of the various steps in transcription. Our Consortium is dedicated to developing and implementing the technology to further this understanding. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
1936122X
Volume :
38
Database :
Academic Search Index
Journal :
Annual Review of Biophysics
Publication Type :
Academic Journal
Accession number :
42121436
Full Text :
https://doi.org/10.1146/annurev.biophys.050708.133728