Na[sup +] Occupancy and Mg[sup 2+] Block of the N-methyl-D-aspartate Receptor Channel.

Authors :: Yongling Zhu
Auerbach, Anthony
Source :: Journal of General Physiology. Mar2001, Vol. 117 Issue 3, p275. 11p. 3 Charts, 6 Graphs.
Publication Year :: 2001
Abstract: Investigates the effect of extracellular and intracellular sodium (Na) on the single-channel kinetics of magnesium (Mg) block in recombinant NR1-NR2B NMDA receptor channels. Association rate constant of Mg; Locations and apparent affinities of the Na-binding sites; Dissociation rate constant of Mg.

Subjects :: *PHYSIOLOGICAL effects of sodium
*MAGNESIUM
*CELL receptors
*BINDING sites
*REACTIVITY (Chemistry)

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