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Targeted disruption of ICAM-1, P-selectin genes improves cardiac function and survival in TNF-Alpha transgenic mice.

Authors :
Graciano, Ana Lia
Bryant, Debora D.
Source :
American Journal of Physiology: Heart & Circulatory Physiology. Apr2001, Vol. 280 Issue 4, pH1464. 8p. 3 Diagrams, 1 Chart, 4 Graphs.
Publication Year :
2001

Abstract

Presents a study which developed a transgenic mouse model in which tumor necrosis factor is overexpressed in the heart under the regulation of a chain promoter. Methodology; Results of the study.

Subjects

Subjects :
*TRANSGENIC mice
*TUMOR necrosis factors
*HEART

Details

Language :
English
ISSN :
03636135
Volume :
280
Issue :
4
Database :
Academic Search Index
Journal :
American Journal of Physiology: Heart & Circulatory Physiology
Publication Type :
Academic Journal
Accession number :
4259358
Full Text :
https://doi.org/10.1152/ajpheart.2001.280.4.H1464
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