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Meningococcal biofilm growth on an abiotic surface - a model for epithelial colonization?

Authors :
O'Dwyer, Cilona A.
Ming-Shi Li
Langford, Paul R.
Kroll, J. Simon
Source :
Microbiology (13500872). Jun2009, Vol. 155 Issue 6, p1940-1952. 13p. 4 Charts, 2 Graphs.
Publication Year :
2009

Abstract

The article presents a study on the possibility of setting the meningococcal biofilm growth as model for epithelial colonization. Neisseria meningitidis (N. meningitidis) invades the human nasopharynx with the possibility of life-threatening infection, and carriage of such is believed to lead to specific meningococal diseases immunity. Such aggregated organisms cling to the epithelial surface of the nasopharynx. A hypothesis is presented wherein the state when aggregated organisms attach to the epithelial surface is the biofilm state, and to further explore the this state, biofilm formation by a serogroup on an abiotic surface of a sorbarod system was investigated.

Details

Language :
English
ISSN :
13500872
Volume :
155
Issue :
6
Database :
Academic Search Index
Journal :
Microbiology (13500872)
Publication Type :
Academic Journal
Accession number :
43007992
Full Text :
https://doi.org/10.1099/mic.0.026559-0