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Role of specific microRNAs for endothelial function and angiogenesis
- Source :
-
Biochemical & Biophysical Research Communications . Sep2009, Vol. 386 Issue 4, p549-553. 5p. - Publication Year :
- 2009
-
Abstract
- Abstract: Accumulating evidence indicates that various aspects of angiogenesis, such as proliferation, migration, and morphogenesis of endothelial cells, can be regulated by specific miRNAs in an endothelial-specific manner. As novel molecular targets, miRNAs have a potential value for treatment of angiogenesis-associated diseases such as cancers, inflammation, and vascular diseases. In this article, we review the latest advances in the identification and validation of angiogenesis-regulatory miRNAs and their targets, and discuss their roles and mechanisms in regulating endothelial cell function and angiogenesis. [Copyright &y& Elsevier]
Details
- Language :
- English
- ISSN :
- 0006291X
- Volume :
- 386
- Issue :
- 4
- Database :
- Academic Search Index
- Journal :
- Biochemical & Biophysical Research Communications
- Publication Type :
- Academic Journal
- Accession number :
- 43319586
- Full Text :
- https://doi.org/10.1016/j.bbrc.2009.06.075