Studies on the oxidation reaction of l-cysteine in a confined matrix of layered double hydroxides

Abstract: The amino acid l-cysteine (l-Cys) was intercalated into a MgAl layered double hydroxide (LDH), and its oxidation reaction by hexacyanoferrate (III) (Fe(CN)6 3−) in the confined region between sheets of LDH has been studied in detail. Based on the measurement results of XRD, Raman and FT-IR, it was found that the interlayer l-Cys was oxidized to cystine by Fe(CN)6 3−. Furthermore, the kinetics of this reaction was investigated in batch mode. The influences of initial Fe(CN)6 3−concentration, l-Cys-LDH quantity and reaction temperature on the interlayer oxidation reaction have been studied, respectively. The reaction follows a diffusion-controlled mechanism represented by Crank-Ginstling and Brounshtein kinetic model with the apparent activation energy of 29.93kJ/mol. Therefore, this layered material may have prospective application as a novel “molecular reactor” for confined chemical reactions. [Copyright &y& Elsevier]