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The Role of Ribose on Oxidative Stress During Hypoxic Exercise: A Pilot Study.
- Source :
-
Journal of Medicinal Food . Jun2009, Vol. 12 Issue 3, p690-693. 4p. - Publication Year :
- 2009
-
Abstract
- AbstractOxygen free radicals are produced during stress, are unstable, and potentially interact with other cellular components or molecules. This reactivity can influence cellular function, including a prolongation in tissue recovery following exercise. We tested the effect of ribose (d-ribose), a pentose carbohydrate, in a double-blinded, crossover study on markers of free radical production during hypoxic exercise. Seven healthy volunteers cycled at their lactate threshold for 25 minutes while inhaling 16% O2with a subsequent 60-minute resting period at room air. Subjects ingested either placebo or 7 g of ribose in 250 mL of water before and after the exercise session. Urinary malondialdehyde (MDA) and plasma reduced glutathione levels increased significantly during placebo ingestion (0.2 ± 0.03 nM/mg and 0.26 ± 0.29 μM, respectively) but were lower with ribose supplementation (0.04 ± 0.03 nM/mg and 0.38 ± 0.29 μM, respectively; P< .05). Uric acid levels were similar between groups (ribose vs. placebo, 4.55 ± 0.06 mg/dL vs. 4.67 ± 0.06 mg/dL). Ribose demonstrated a beneficial trend in lower MDA and reduced glutathione levels during hypoxic stress. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 1096620X
- Volume :
- 12
- Issue :
- 3
- Database :
- Academic Search Index
- Journal :
- Journal of Medicinal Food
- Publication Type :
- Academic Journal
- Accession number :
- 43794275
- Full Text :
- https://doi.org/10.1089/jmf.2008.0065