CREG promotes a mature smooth muscle cell phenotype and reduces neointimal formation in balloon-injured rat carotid artery.

Authors :: Yaling Han
Jie Deng
Liang Guo
Chenghui Yan
Ming Liang
Jian Kang
Haiwei Liu
Graham, Alan M.
Shaohua Li
Source :: Cardiovascular Research. Jun2008, Vol. 78 Issue 3, p597-604. 8p. 6 Graphs.
Publication Year :: 2008
Abstract: Aim: We previously showed that cellular repressor of E1A-stimulated genes (CREG) is up-regulated during serum starvation-induced vascular smooth muscle cell (SMC) differentiation. The aim of this study was to determine the role of CREG in maintaining the quiescent, differentiated phenotype of SMCs both in culture and in balloon-injured rat carotid artery. [ABSTRACT FROM PUBLISHER]

Subjects :: *SMOOTH muscle
*PHENOTYPES
*CAROTID artery injuries
*RATS
*VASCULAR smooth muscle

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