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After BRCA1 and BRCA2--What Next? Multifactorial Segregation Analyses of Three-Generation, Population-Based Australian Families Affected by Female Breast Cancer.

Authors :
Cui, Jisheng
Dite, Gillian S.
Hopper, John L.
Giles, Graham G.
Antoniou, Antonis C.
Easton, Douglas F.
Southey, Melissa C.
Venter, Deon J.
McCredie, Margaret R. E.
Source :
American Journal of Human Genetics. Feb2001, Vol. 68 Issue 2, p420-431. 12p. 1 Diagram, 2 Graphs.
Publication Year :
2001

Abstract

Presents segregation analyses which investigated models of familial aggregation of female breast cancer that consider together different modes of inheritance in Australia. Percentage of women with breast cancer by age at diagnosis for different categories of family members; Cumulative probability of breast cancer for the Australian population; Comparison between the segregation analyses of two-locus models and the single-locus models.

Subjects

Subjects :
*BREAST cancer
*FAMILIAL diseases

Details

Language :
English
ISSN :
00029297
Volume :
68
Issue :
2
Database :
Academic Search Index
Journal :
American Journal of Human Genetics
Publication Type :
Academic Journal
Accession number :
4441200
Full Text :
https://doi.org/10.1086/318187