IRM fonctionnelle : nouvel outil pour prédire la réponse des cancers du col utérin à la chimioradiothérapie concomitante ?

Abstract: The treatment of advanced cervix is concomitant radiochemotherapy. Local prognosis and global survival depend on tumoral volume, locoregional extension and radio sensitivity of the lesion. This one is function of tumoral hypoxia, tumoral interstitial pressure and existence of an anaemia. DCE-MRI allows to quantify pilot vascular parameters of the first two factors. Combined analysis: tumoral volume, anaemia and vascular parameters before and in the course of treatment allows a strong correlation with the risk of local recurrence and global survival. [Copyright &y& Elsevier]