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The Influence of the Recipient's Body Weight on the Probability to Obtain a Heart Transplant—POLKARD HF Registry
- Source :
-
Transplantation Proceedings . Oct2009, Vol. 41 Issue 8, p3166-3170. 5p. - Publication Year :
- 2009
-
Abstract
- Abstract: Introduction: The aim of the study was to analyze the influence of body weight of the adult heart recipient on the chance to obtain a transplant. Methods: We analyzed the data from all 658 patients listed for heart transplantation. Results: During the follow-up period, 325 (49%) of listed patients underwent transplantation with 102 (15%) succumbing before heart transplantation. The mean weight of transplanted patients was 73.7 ± 13.7 kg and 81.2 ± 15.4 kg for those not transplanted (P < .00001). Patients were divided according to body weight in two groups: light = below 80 kg (n = 360) or heavy ≥ 80 kg or above (n = 297). On the transplant list, 111 heavy patients (37%) versus 213 light patients (59%) underwent the procedure, a significant difference. The waiting time among light patients was 255 versus heavy patients of 395 days (P < .005). There was a similar number of deaths before transplantation among the light (n = 56 360 patients; 15.5%) versus the heavy group (49/297; 16%). Upon multivariate Cox mode analysis independent factors related to not receiving a heart transplant were greater weight, systolic blood pressure, pulmonary vascular resistance, Heart Failure Survival Score (HFSS) score and lower N-terminal pro-brain natriuretic peptide (NTproBNP) levels. Conclusions: Among adult heart transplant candidates, the chance to receive a heart transplant significantly decreased when the recipient''s weight exceeded 80 kg. Patients with a body weight more than 110 kg had a poor chance to receive a heart transplantation. [Copyright &y& Elsevier]
Details
- Language :
- English
- ISSN :
- 00411345
- Volume :
- 41
- Issue :
- 8
- Database :
- Academic Search Index
- Journal :
- Transplantation Proceedings
- Publication Type :
- Academic Journal
- Accession number :
- 44827385
- Full Text :
- https://doi.org/10.1016/j.transproceed.2009.08.015