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Random Intracellular Drift Explains the Clonal Expansion of Mitochondrial DNA Mutations with Age.

Authors :
Elson, J. L.
Samuels, D. C.
Turnbull, D. M.
Chinnery, P. F.
Source :
American Journal of Human Genetics. Mar2001, Vol. 68 Issue 3, p802. 5p. 1 Diagram.
Publication Year :
2001

Abstract

Presents information on a study which explained the clonal expansion of somatic mitochondrial DNA mutations with age. Role of random intracellular drift; Methodology; Results and discussion.

Subjects

Subjects :
*MITOCHONDRIAL DNA
*GENETIC mutation

Details

Language :
English
ISSN :
00029297
Volume :
68
Issue :
3
Database :
Academic Search Index
Journal :
American Journal of Human Genetics
Publication Type :
Academic Journal
Accession number :
4486873
Full Text :
https://doi.org/10.1086/318801
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