Deazaflavins as mediators in light-driven cytochrome P450 catalyzed hydroxylationsElectronic supplementary information (ESI) available: Experimental details and additional control experiments. See DOI: 10.1039/b913863c.

Authors :: Felipe E. ZillyThese authors contributed equally to this paper.
Andreas Taglieber
Frank Schulz
Frank Hollmann
Manfred T. Reetz
Source :: Chemical Communications. Nov2009, Vol. 2009 Issue 46, p7152-7154. 3p.
Publication Year :: 2009
Abstract: A light-driven deazaflavin-dependent direct enzyme regeneration system has been developed for a P450-BM3 catalyzed CH-activating hydroxylation, thereby avoiding the need for the expensive NADPH cofactor. [ABSTRACT FROM AUTHOR]

Subjects :: *FLAVINS
*CYTOCHROME P-450
*ADENINE nucleotides
*HYDROXYLATION
*ENZYME activation

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