The Effect of Myo-Inositol on Ethanol-Induced Metabolic Changesand Insulin Concentration in the Rat.

Myo-inositol was found to possess several beneficial effects on theorganism. The effect of myo-inositol on ethanol-induced metabolic changesand insulin concentration was investigated in growing rats. The increase inliver triglycerides induced by ethanol drinking (10% ethanol solution as theonly drinking fluid for 10 days) was completely abolished by simultaneoustreatment with myo-inositol (0.1 g/100 g b.w., every day given intragastrically).The ethanol-evoked decrease in blood insulin and the increase in liver glycogenwere also partially prevented by myo-inositol. Myo-inositol did not causeany undesirable metabolic changes in the rats. The results indicate that myo-inositolmay be useful in the treatment of some metabolic consequences of alcohol drinking. [ABSTRACT FROM AUTHOR]