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Contraindicated Medication Use in Dialysis Patients Undergoing Percutaneous Coronary Intervention.

Authors :
Tsai, Thomas T.
Maddox, Thomas M.
Roe, Matthew T.
Dai, David
Alexander, Karen P.
Ho, P. Michael
Messenger, John C.
Nallamothu, Brahmajee K.
Peterson, Eric D.
Rumsfeld, John S.
Source :
JAMA: Journal of the American Medical Association. 12/9/2009, Vol. 302 Issue 22, p2458-2464. 7p. 2 Diagrams, 3 Charts.
Publication Year :
2009

Abstract

The article focuses on a study which examined the administration of contraindicated drugs enoxaparin and eptifibatide among dialysis patients who are undergoing percutaneous coronary intervention (PCI). The study included 22,778 dialysis patients who underwent PCI between January 1, 2004 and August 31, 2008 in the U.S. Study population was randomized to either receive enoxaparin, eptifibatide or both. Study authors found that patients who received contraindicated antithrombotics had higher risks of in-hospital bleeding and mortality.

Details

Language :
English
ISSN :
00987484
Volume :
302
Issue :
22
Database :
Academic Search Index
Journal :
JAMA: Journal of the American Medical Association
Publication Type :
Academic Journal
Accession number :
45660513
Full Text :
https://doi.org/10.1001/jama.2009.1800