Flexible synthesis, structural determination, and synthetic application of a new C1-symmetric chiral ammonium betaineElectronic supplementary information (ESI) available: Experimental procedures, characterization data of 1–14, and details of X-ray crystallographic analysis of 1aand anti-13. CCDC 744059& 744058. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/b916627k

A C1-symmetric chiral ammonium betaine has been developed, and its intramolecular ion-pairing structure in solid state and its catalytic performance to achieve the highly stereoselective Mannich-type reaction of 2-alkoxythiazol-5(4H)-ones are revealed. [ABSTRACT FROM AUTHOR]