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Improved Secretion of Native Human Insulin-Like Growth Factor 1 from gas1 Mutant Saccharomyces....
- Source :
-
Applied & Environmental Microbiology . Dec2000, Vol. 66 Issue 12, p5477. 3p. 1 Black and White Photograph, 2 Graphs. - Publication Year :
- 2000
-
Abstract
- Examines the secretion of human insulin-like growth factor 1 (hIGF-1) from mutant Saccharomyces cerevisiae cells. Fusion of hIGF-1 gene to mating factor alpha prepro-leader sequence; Inactivation of gas1 gene; Development of a supersecretory phenotype; Production of heterologous protein.
- Subjects :
- *SOMATOMEDIN
*SACCHAROMYCES cerevisiae
Subjects
Details
- Language :
- English
- ISSN :
- 00992240
- Volume :
- 66
- Issue :
- 12
- Database :
- Academic Search Index
- Journal :
- Applied & Environmental Microbiology
- Publication Type :
- Academic Journal
- Accession number :
- 4771571
- Full Text :
- https://doi.org/10.1128/AEM.66.12.5477-5479.2000