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Why CD8+ T Cells Need Diversity When Growing Up
- Source :
-
Immunity (10747613) . Jan2010, Vol. 32 Issue 1, p5-6. 2p. - Publication Year :
- 2010
-
Abstract
- A thymus-specific subunit of the proteasome, β5t, was previously described and shown to be essential for positive selection of CD8+ T cells. In this issue of Immunity, suggest that β5t is essential because it alters the specific peptide-MHC complexes displayed by cortical epithelial cells. [Copyright &y& Elsevier]
- Subjects :
- *GLYCOPROTEINS
*CELL growth
*PEPTIDES
*EPITHELIAL cells
*T cells
Subjects
Details
- Language :
- English
- ISSN :
- 10747613
- Volume :
- 32
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- Immunity (10747613)
- Publication Type :
- Academic Journal
- Accession number :
- 47827837
- Full Text :
- https://doi.org/10.1016/j.immuni.2010.01.005